SOST FISH Probe
The SOST FISH probe is designed to hybridize to the SOST gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SOST-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SOST-20-RE | 20 (40 μL) | 200 μL |  |
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| SOST-20-GO | 20 (40 μL) | 200 μL |  |
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| SOST-20-GR | 20 (40 μL) | 200 μL |  |
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| SOST-20-AQ | 20 (40 μL) | 200 μL |  |
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| SOST-20-DIG | 20 (40 μL) | 200 μL |  |
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| SOST-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SOST
Gene Name: Sclerostin
Chromosome: CHR17: 41831098-41836156
Locus: 17q21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: SOST FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SOST-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping