SORCS3 Break Apart FISH Probe
Empire Genomics’ SORCS3 Break Apart FISH Probe is designed to flank the SORCS3 gene and is typically used for detecting SORCS3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SORCS3BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SORCS3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| SORCS3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| SORCS3BA-20-GORE | 20 (40 μL) | 200 μL |
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| SORCS3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| SORCS3BA-20-GROR | 20 (40 μL) | 200 μL |
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| SORCS3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| SORCS3BA-20-REGO | 20 (40 μL) | 200 μL |
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| SORCS3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a type-I receptor transmembrane protein that is a member of the vacuolar protein sorting 10 receptor family. Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus. The N-terminal segment of this domain has a consensus motif for proprotein convertase processing, and the C-terminal segment of this domain is characterized by ten conserved cysteine residues. The vacuolar protein sorting 10 domain is followed by a leucine-rich segment, a transmembrane domain, and a short C-terminal cytoplasmic domain that interacts with adaptor molecules. The transcript is expressed at high levels in the brain, and candidate gene studies suggest that genetic variation in this gene is associated with Alzheimer's disease. Consistent with this observation, knockdown of the gene in cell culture results in an increase in amyloid precursor protein processing. [provided by RefSeq, Dec 2014]
Gene Details
Gene Symbol: SORCS3
Gene Name: Sortilin Related VPS10 Domain Containing Receptor 3
Chromosome: CHR10: 106400858-107024993
Locus: 10q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SORCS3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SORCS3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping