SNX15 Break Apart FISH Probe
Empire Genomics’ SNX15 Break Apart FISH Probe is designed to flank the SNX15 gene and is typically used for detecting SNX15 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SNX15BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SNX15BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SNX15BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SNX15BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SNX15BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SNX15BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SNX15BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SNX15BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SNX15BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010]
Gene Details
Gene Symbol: SNX15
Gene Name: Sorting Nexin 15
Chromosome: CHR11: 64794879-64808044
Locus: 11q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: SNX15 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SNX15-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping