SNRPN Break Apart FISH Probe
Empire Genomics’ SNRPN Break Apart FISH Probe is designed to flank the SNRPN gene and is typically used for detecting SNRPN rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SNRPNBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SNRPNBA-20-AQOR | 20 (40 μL) | 200 μL |
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| SNRPNBA-20-GOGR | 20 (40 μL) | 200 μL |
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| SNRPNBA-20-GORE | 20 (40 μL) | 200 μL |
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| SNRPNBA-20-GRGO | 20 (40 μL) | 200 μL |
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| SNRPNBA-20-GROR | 20 (40 μL) | 200 μL |
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| SNRPNBA-20-GRRE | 20 (40 μL) | 200 μL |
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| SNRPNBA-20-REGO | 20 (40 μL) | 200 μL |
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| SNRPNBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: SNRPN
Gene Name: Small Nuclear Ribonucleoprotein Polypeptide N
Chromosome: CHR15: 25068793-25223729
Locus: 15q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SNRPN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SNRPN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping