SMP-1 FISH Probe
The SMP-1 FISH probe is designed to hybridize to the SMP-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPAG8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPAG8-20-RE | 20 (40 μL) | 200 μL |  |
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| SPAG8-20-GO | 20 (40 μL) | 200 μL |  |
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| SPAG8-20-GR | 20 (40 μL) | 200 μL |  |
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| SPAG8-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPAG8-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPAG8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: SPAG8
Gene Name: Sperm Associated Antigen 8
Chromosome: CHR9: 35807781-35812259
Locus: 9p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SMP-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPAG8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping