SMOX FISH Probe
The SMOX FISH probe is designed to hybridize to the SMOX gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SMOX-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
SMOX-20-RE | 20 (40 μL) | 200 μL | ||
SMOX-20-GO | 20 (40 μL) | 200 μL | ||
SMOX-20-GR | 20 (40 μL) | 200 μL | ||
SMOX-20-AQ | 20 (40 μL) | 200 μL | ||
SMOX-20-DIG | 20 (40 μL) | 200 μL | ||
SMOX-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: SMOX
Gene Name: Spermine Oxidase
Chromosome: CHR20: 4129449-4168369
Locus: 20p13
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SMOX FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SMOX-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping