SMAM1 FISH Probe
The SMAM1 FISH probe is designed to hybridize to the SMAM1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SERF1A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SERF1A-20-RE | 20 (40 μL) | 200 μL |  |
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| SERF1A-20-GO | 20 (40 μL) | 200 μL |  |
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| SERF1A-20-GR | 20 (40 μL) | 200 μL |  |
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| SERF1A-20-AQ | 20 (40 μL) | 200 μL |  |
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| SERF1A-20-DIG | 20 (40 μL) | 200 μL |  |
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| SERF1A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known; however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SERF1A
Gene Name: Small EDRK-rich Factor 1A
Chromosome: CHR5: 69321071-69338940
Locus: 5q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SMAM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SERF1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping