SLC8A1 FISH Probe
The SLC8A1 FISH probe is designed to hybridize to the SLC8A1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC8A1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| SLC8A1-20-RE | 20 (40 μL) | 200 μL |  |
|
| SLC8A1-20-GO | 20 (40 μL) | 200 μL |  |
|
| SLC8A1-20-GR | 20 (40 μL) | 200 μL |  |
|
| SLC8A1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| SLC8A1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| SLC8A1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004]
Gene Details
Gene Symbol: SLC8A1
Gene Name: Solute Carrier Family 8 Member A1
Chromosome: CHR2: 40339285-40739575
Locus: 2p22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: SLC8A1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SLC8A1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping