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SLC46A1 FISH Probe

The SLC46A1 FISH probe is designed to hybridize to the SLC46A1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
SLC46A1-20-OR  (Standard Design) 20 (40 μL) 200 μL
SLC46A1-20-RE 20 (40 μL) 200 μL
SLC46A1-20-GO 20 (40 μL) 200 μL
SLC46A1-20-GR 20 (40 μL) 200 μL
SLC46A1-20-AQ 20 (40 μL) 200 μL
SLC46A1-20-DIG 20 (40 μL) 200 μL
SLC46A1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]

Gene Details

Gene Symbol: SLC46A1

Gene Name: Solute Carrier Family 46 Member 1

Chromosome: CHR17: 26721660-26733230

Locus: 17q11.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: SLC46A1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SLC46A1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping