SLC12A3 FISH Probe
The SLC12A3 FISH probe is designed to hybridize to the SLC12A3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC12A3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SLC12A3-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC12A3-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC12A3-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC12A3-20-AQ | 20 (40 μL) | 200 μL |  |
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| SLC12A3-20-DIG | 20 (40 μL) | 200 μL |  |
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| SLC12A3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SLC12A3
Gene Name: Solute Carrier Family 12 Member 3
Chromosome: CHR16: 56899118-56949762
Locus: 16q13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SLC12A3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SLC12A3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping