SKAP2 Break Apart FISH Probe
Empire Genomics’ SKAP2 Break Apart FISH Probe is designed to flank the SKAP2 gene and is typically used for detecting SKAP2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SKAP2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SKAP2BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SKAP2BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SKAP2BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SKAP2BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SKAP2BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SKAP2BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| SKAP2BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SKAP2BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: SKAP2
Gene Name: Src Kinase Associated Phosphoprotein 2
Chromosome: CHR7: 26706687-26904341
Locus: 7p15.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: SKAP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SKAP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping