SIRPA Break Apart FISH Probe
Empire Genomics’ SIRPA Break Apart FISH Probe is designed to flank the SIRPA gene and is typically used for detecting SIRPA rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SIRPABA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SIRPABA-20-AQOR | 20 (40 μL) | 200 μL |
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| SIRPABA-20-GOGR | 20 (40 μL) | 200 μL |
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| SIRPABA-20-GORE | 20 (40 μL) | 200 μL |
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| SIRPABA-20-GRGO | 20 (40 μL) | 200 μL |
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| SIRPABA-20-GROR | 20 (40 μL) | 200 μL |
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| SIRPABA-20-GRRE | 20 (40 μL) | 200 μL |
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| SIRPABA-20-REGO | 20 (40 μL) | 200 μL |
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| SIRPABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SIRPA
Gene Name: Signal Regulatory Protein Alpha
Chromosome: CHR20: 1874812-1920540
Locus: 20p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SIRPA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SIRPA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping