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SIMO FISH Probe

The SIMO FISH probe is designed to hybridize to the SIMO gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PAX6DRR-20-OR  (Standard Design) 20 (40 μL) 200 μL
PAX6DRR-20-RE 20 (40 μL) 200 μL
PAX6DRR-20-GO 20 (40 μL) 200 μL
PAX6DRR-20-GR 20 (40 μL) 200 μL
PAX6DRR-20-AQ 20 (40 μL) 200 μL
PAX6DRR-20-DIG 20 (40 μL) 200 μL
PAX6DRR-20-BIO 20 (40 μL) 200 μL

Gene Summary

This region represents a cluster of enhancers located approximately 100 kb downstream of the PAX6 (paired box 6) gene. It includes multiple highly conserved regions and DNase I hypersensitive sites. One of these conserved regions, called SIMO, includes a binding site for the Pax6 protein and is important for establishing an autoregulatory feedback loop for PAX6 expression. Deletion, mutation, or chromosomal rearrangement of this region can phenocopy mutation in the PAX6 gene and result in aniridia. [provided by RefSeq, Sep 2016]

Gene Details

Gene Symbol: PAX6DRR

Gene Name: PAX6 Downstream Regulatory Region

Locus: 11p13

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: SIMO FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PAX6DRR-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping