SIM2 Break Apart FISH Probe
Empire Genomics’ SIM2 Break Apart FISH Probe is designed to flank the SIM2 gene and is typically used for detecting SIM2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SIM2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
SIM2BA-20-AQOR | 20 (40 μL) | 200 μL | ||
SIM2BA-20-GOGR | 20 (40 μL) | 200 μL | ||
SIM2BA-20-GORE | 20 (40 μL) | 200 μL | ||
SIM2BA-20-GRGO | 20 (40 μL) | 200 μL | ||
SIM2BA-20-GROR | 20 (40 μL) | 200 μL | ||
SIM2BA-20-GRRE | 20 (40 μL) | 200 μL | ||
SIM2BA-20-REGO | 20 (40 μL) | 200 μL | ||
SIM2BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Gene Details
Gene Symbol: SIM2
Gene Name: Single-minded Family BHLH Transcription Factor 2
Chromosome: CHR21: 38071990-38122510
Locus: 21q22.13
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: SIM2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SIM2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping