SIM2 FISH Probe
The SIM2 FISH probe is designed to hybridize to the SIM2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SIM2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SIM2-20-RE | 20 (40 μL) | 200 μL |  |
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| SIM2-20-GO | 20 (40 μL) | 200 μL |  |
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| SIM2-20-GR | 20 (40 μL) | 200 μL |  |
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| SIM2-20-AQ | 20 (40 μL) | 200 μL |  |
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| SIM2-20-DIG | 20 (40 μL) | 200 μL |  |
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| SIM2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Gene Details
Gene Symbol: SIM2
Gene Name: Single-minded Family BHLH Transcription Factor 2
Chromosome: CHR21: 38071990-38122510
Locus: 21q22.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SIM2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SIM2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping