SHANK2 FISH Probe
The SHANK2 FISH probe is designed to hybridize to the SHANK2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SHANK2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SHANK2-20-RE | 20 (40 μL) | 200 μL |  |
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| SHANK2-20-GO | 20 (40 μL) | 200 μL |  |
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| SHANK2-20-GR | 20 (40 μL) | 200 μL |  |
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| SHANK2-20-AQ | 20 (40 μL) | 200 μL |  |
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| SHANK2-20-DIG | 20 (40 μL) | 200 μL |  |
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| SHANK2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Details
Gene Symbol: SHANK2
Gene Name: SH3 And Multiple Ankyrin Repeat Domains 2
Chromosome: CHR11: 70313960-70935808
Locus: 11q13.3-q13.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SHANK2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SHANK2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping