SH3BP1 Break Apart FISH Probe
Empire Genomics’ SH3BP1 Break Apart FISH Probe is designed to flank the SH3BP1 gene and is typically used for detecting SH3BP1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SH3BP1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SH3BP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| SH3BP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| SH3BP1BA-20-GORE | 20 (40 μL) | 200 μL |
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| SH3BP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| SH3BP1BA-20-GROR | 20 (40 μL) | 200 μL |
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| SH3BP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| SH3BP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| SH3BP1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein's association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: SH3BP1
Gene Name: SH3 Domain Binding Protein 1
Chromosome: CHR22: 38035683-38052050
Locus: 22q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SH3BP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SH3BP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping