SFTPB FISH Probe
The SFTPB FISH probe is designed to hybridize to the SFTPB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SFTPB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SFTPB-20-RE | 20 (40 μL) | 200 μL |  |
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| SFTPB-20-GO | 20 (40 μL) | 200 μL |  |
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| SFTPB-20-GR | 20 (40 μL) | 200 μL |  |
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| SFTPB-20-AQ | 20 (40 μL) | 200 μL |  |
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| SFTPB-20-DIG | 20 (40 μL) | 200 μL |  |
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| SFTPB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]
Gene Details
Gene Symbol: SFTPB
Gene Name: Surfactant Protein B
Chromosome: CHR2: 85884439-85895864
Locus: 2p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SFTPB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SFTPB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping