SF3B3 Break Apart FISH Probe
Empire Genomics’ SF3B3 Break Apart FISH Probe is designed to flank the SF3B3 gene and is typically used for detecting SF3B3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SF3B3BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SF3B3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| SF3B3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| SF3B3BA-20-GORE | 20 (40 μL) | 200 μL |
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| SF3B3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| SF3B3BA-20-GROR | 20 (40 μL) | 200 μL |
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| SF3B3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| SF3B3BA-20-REGO | 20 (40 μL) | 200 μL |
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| SF3B3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SF3B3
Gene Name: Splicing Factor 3b Subunit 3
Chromosome: CHR16: 70557690-70611571
Locus: 16q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SF3B3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SF3B3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping