SF3B1 Break Apart FISH Probe
Empire Genomics’ SF3B1 Break Apart FISH Probe is designed to flank the SF3B1 gene and is typically used for detecting SF3B1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SF3B1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SF3B1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SF3B1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SF3B1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SF3B1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SF3B1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SF3B1BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| SF3B1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SF3B1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SF3B1
Gene Name: Splicing Factor 3b Subunit 1
Chromosome: CHR2: 198256697-198299771
Locus: 2q33.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: SF3B1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SF3B1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping