SESN1 FISH Probe
The SESN1 FISH probe is designed to hybridize to the SESN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SESN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SESN1-20-RE | 20 (40 μL) | 200 μL |  |
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| SESN1-20-GO | 20 (40 μL) | 200 μL |  |
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| SESN1-20-GR | 20 (40 μL) | 200 μL |  |
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| SESN1-20-AQ | 20 (40 μL) | 200 μL |  |
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| SESN1-20-DIG | 20 (40 μL) | 200 μL |  |
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| SESN1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Details
Gene Symbol: SESN1
Gene Name: Sestrin 1
Chromosome: CHR6: 109307639-109415708
Locus: 6q21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SESN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SESN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping