SERF1A Break Apart FISH Probe
Empire Genomics’ SERF1A Break Apart FISH Probe is designed to flank the SERF1A gene and is typically used for detecting SERF1A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SERF1ABA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SERF1ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| SERF1ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| SERF1ABA-20-GORE | 20 (40 μL) | 200 μL |
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| SERF1ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| SERF1ABA-20-GROR | 20 (40 μL) | 200 μL |
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| SERF1ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| SERF1ABA-20-REGO | 20 (40 μL) | 200 μL |
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| SERF1ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known; however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SERF1A
Gene Name: Small EDRK-rich Factor 1A
Chromosome: CHR5: 69321071-69338940
Locus: 5q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SERF1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SERF1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping