SEPW FISH Probe
The SEPW FISH probe is designed to hybridize to the SEPW gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SELENOW-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SELENOW-20-RE | 20 (40 μL) | 200 μL |  |
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| SELENOW-20-GO | 20 (40 μL) | 200 μL |  |
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| SELENOW-20-GR | 20 (40 μL) | 200 μL |  |
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| SELENOW-20-AQ | 20 (40 μL) | 200 μL |  |
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| SELENOW-20-DIG | 20 (40 μL) | 200 μL |  |
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| SELENOW-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is highly expressed in skeletal muscle, heart and brain. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Studies in mouse show that this selenoprotein is involved in muscle growth and differentiation, and in the protection of neurons from oxidative stress during neuronal development. A retroprocessed pseudogene of this locus has been identified on chromosome 1. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: SELENOW
Gene Name: Selenoprotein W
Chromosome: CHR19: 47778584-47784681
Locus: 19q13.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SEPW FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SELENOW-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping