SEPHS2 Break Apart FISH Probe
Empire Genomics’ SEPHS2 Break Apart FISH Probe is designed to flank the SEPHS2 gene and is typically used for detecting SEPHS2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEPHS2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEPHS2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| SEPHS2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| SEPHS2BA-20-GORE | 20 (40 μL) | 200 μL |
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| SEPHS2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| SEPHS2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| SEPHS2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| SEPHS2BA-20-REGO | 20 (40 μL) | 200 μL |
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| SEPHS2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes an enzyme that catalyzes the production of monoselenophosphate (MSP) from selenide and ATP. MSP is the selenium donor required for synthesis of selenocysteine (Sec), which is co-translationally incorporated into selenoproteins at in-frame UGA codons that normally signal translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is itself a selenoprotein containing a Sec residue at its active site, suggesting the existence of an autoregulatory mechanism. It is preferentially expressed in tissues implicated in the synthesis of selenoproteins and in sites of blood cell development. A pseudogene for this locus has been identified on chromosome 5. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: SEPHS2
Gene Name: Selenophosphate Synthetase 2
Chromosome: CHR16: 30454951-30457224
Locus: 16p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SEPHS2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SEPHS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping