SELENOK FISH Probe
The SELENOK FISH probe is designed to hybridize to the SELENOK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SELENOK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SELENOK-20-RE | 20 (40 μL) | 200 μL |  |
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| SELENOK-20-GO | 20 (40 μL) | 200 μL |  |
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| SELENOK-20-GR | 20 (40 μL) | 200 μL |  |
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| SELENOK-20-AQ | 20 (40 μL) | 200 μL |  |
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| SELENOK-20-DIG | 20 (40 μL) | 200 μL |  |
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| SELENOK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the selenoprotein K family. It is a transmembrane protein that is localized in the endoplasmic reticulum (ER), and is involved in ER-associated degradation (ERAD) of misfolded, glycosylated proteins. It also has a role in the protection of cells from ER stress-induced apoptosis. Knockout studies in mice show the importance of this gene in promoting Ca(2+) flux in immune cells and mounting effective immune response. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Pseudogenes of this locus have been identified on chromosomes 6 and 19.[provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: SELENOK
Gene Name: Selenoprotein K
Chromosome: CHR3: 53891961-53885198
Locus: 3p21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SELENOK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SELENOK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping