SCN1A Break Apart FISH Probe
Empire Genomics’ SCN1A Break Apart FISH Probe is designed to flank the SCN1A gene and is typically used for detecting SCN1A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCN1ABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCN1ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| SCN1ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| SCN1ABA-20-GORE | 20 (40 μL) | 200 μL |
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| SCN1ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| SCN1ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| SCN1ABA-20-ORGR | 20 (40 μL) | 200 μL |
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| SCN1ABA-20-REGO | 20 (40 μL) | 200 μL |
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| SCN1ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: SCN1A
Gene Name: Sodium Voltage-gated Channel Alpha Subunit 1
Chromosome: CHR2: 166845669-167005642
Locus: 2q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SCN1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SCN1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping