SCN1A FISH Probe
The SCN1A FISH probe is designed to hybridize to the SCN1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SCN1A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SCN1A-20-RE | 20 (40 μL) | 200 μL |  |
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| SCN1A-20-GO | 20 (40 μL) | 200 μL |  |
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| SCN1A-20-GR | 20 (40 μL) | 200 μL |  |
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| SCN1A-20-AQ | 20 (40 μL) | 200 μL |  |
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| SCN1A-20-DIG | 20 (40 μL) | 200 μL |  |
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| SCN1A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: SCN1A
Gene Name: Sodium Voltage-gated Channel Alpha Subunit 1
Chromosome: CHR2: 166845669-167005642
Locus: 2q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SCN1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SCN1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping