SCARB2 FISH Probe
The SCARB2 FISH probe is designed to hybridize to the SCARB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SCARB2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SCARB2-20-RE | 20 (40 μL) | 200 μL |  |
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| SCARB2-20-GO | 20 (40 μL) | 200 μL |  |
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| SCARB2-20-GR | 20 (40 μL) | 200 μL |  |
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| SCARB2-20-AQ | 20 (40 μL) | 200 μL |  |
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| SCARB2-20-DIG | 20 (40 μL) | 200 μL |  |
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| SCARB2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: SCARB2
Gene Name: Scavenger Receptor Class B Member 2
Chromosome: CHR4: 77079891-77135052
Locus: 4q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SCARB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SCARB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping