SAV1 FISH Probe
The SAV1 FISH probe is designed to hybridize to the SAV1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SAV1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
SAV1-20-RE | 20 (40 μL) | 200 μL | ||
SAV1-20-GO | 20 (40 μL) | 200 μL | ||
SAV1-20-GR | 20 (40 μL) | 200 μL | ||
SAV1-20-AQ | 20 (40 μL) | 200 μL | ||
SAV1-20-DIG | 20 (40 μL) | 200 μL | ||
SAV1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]
Gene Details
Gene Symbol: SAV1
Gene Name: Salvador Family WW Domain Containing Protein 1
Chromosome: CHR14: 51100359-51135023
Locus: 14q22.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SAV1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SAV1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping