SART-1 FISH Probe
The SART-1 FISH probe is designed to hybridize to the SART-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SART1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SART1-20-RE | 20 (40 μL) | 200 μL |  |
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| SART1-20-GO | 20 (40 μL) | 200 μL |  |
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| SART1-20-GR | 20 (40 μL) | 200 μL |  |
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| SART1-20-AQ | 20 (40 μL) | 200 μL |  |
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| SART1-20-DIG | 20 (40 μL) | 200 μL |  |
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| SART1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SART1
Gene Name: SART1, U4/U6.U5 Tri-snRNP-associated Protein 1
Chromosome: CHR11: 65729159-65747607
Locus: 11q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SART-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SART1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping