RYK FISH Probe
The RYK FISH probe is designed to hybridize to the RYK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RYK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RYK-20-RE | 20 (40 μL) | 200 μL |  |
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| RYK-20-GO | 20 (40 μL) | 200 μL |  |
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| RYK-20-GR | 20 (40 μL) | 200 μL |  |
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| RYK-20-AQ | 20 (40 μL) | 200 μL |  |
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| RYK-20-DIG | 20 (40 μL) | 200 μL |  |
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| RYK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
Gene Details
Gene Symbol: RYK
Gene Name: Receptor-like Tyrosine Kinase
Chromosome: CHR3: 133875977-133969586
Locus: 3q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RYK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RYK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping