RUBCN FISH Probe
The RUBCN FISH probe is designed to hybridize to the RUBCN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RUBCN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RUBCN-20-RE | 20 (40 μL) | 200 μL |  |
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| RUBCN-20-GO | 20 (40 μL) | 200 μL |  |
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| RUBCN-20-GR | 20 (40 μL) | 200 μL |  |
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| RUBCN-20-AQ | 20 (40 μL) | 200 μL |  |
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| RUBCN-20-DIG | 20 (40 μL) | 200 μL |  |
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| RUBCN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: RUBCN
Gene Name: RUN And Cysteine Rich Domain Containing Beclin 1 Interacting Protein
Chromosome: CHR3: 197749850-197670212
Locus: 3q29
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RUBCN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RUBCN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping