RTKN FISH Probe
The RTKN FISH probe is designed to hybridize to the RTKN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RTKN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RTKN-20-RE | 20 (40 μL) | 200 μL |  |
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| RTKN-20-GO | 20 (40 μL) | 200 μL |  |
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| RTKN-20-GR | 20 (40 μL) | 200 μL |  |
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| RTKN-20-AQ | 20 (40 μL) | 200 μL |  |
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| RTKN-20-DIG | 20 (40 μL) | 200 μL |  |
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| RTKN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RTKN
Gene Name: Rhotekin
Chromosome: CHR2: 74652987-74669060
Locus: 2p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RTKN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RTKN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping