RRM2B Break Apart FISH Probe
Empire Genomics’ RRM2B Break Apart FISH Probe is designed to flank the RRM2B gene and is typically used for detecting RRM2B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
RRM2BBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
RRM2BBA-20-AQOR | 20 (40 μL) | 200 μL | ||
RRM2BBA-20-GOGR | 20 (40 μL) | 200 μL | ||
RRM2BBA-20-GORE | 20 (40 μL) | 200 μL | ||
RRM2BBA-20-GRGO | 20 (40 μL) | 200 μL | ||
RRM2BBA-20-GRRE | 20 (40 μL) | 200 μL | ||
RRM2BBA-20-ORGR | 20 (40 μL) | 200 μL | ||
RRM2BBA-20-REGO | 20 (40 μL) | 200 μL | ||
RRM2BBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
Gene Details
Gene Symbol: RRM2B
Gene Name: Ribonucleotide Reductase Regulatory TP53 Inducible Subunit M2B
Chromosome: CHR8: 103216728-103251346
Locus: 8q22.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: RRM2B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RRM2B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping