RPSA FISH Probe
The RPSA FISH probe is designed to hybridize to the RPSA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RPSA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RPSA-20-RE | 20 (40 μL) | 200 μL |  |
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| RPSA-20-GO | 20 (40 μL) | 200 μL |  |
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| RPSA-20-GR | 20 (40 μL) | 200 μL |  |
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| RPSA-20-AQ | 20 (40 μL) | 200 μL |  |
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| RPSA-20-DIG | 20 (40 μL) | 200 μL |  |
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| RPSA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RPSA
Gene Name: Ribosomal Protein SA
Chromosome: CHR3: 39448203-39454032
Locus: 3p22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RPSA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RPSA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping