RP35 Break Apart FISH Probe
Empire Genomics’ RP35 Break Apart FISH Probe is designed to flank the RP35 gene and is typically used for detecting RP35 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RP35BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| RP35BA-20-AQOR | 20 (40 μL) | 200 μL |
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| RP35BA-20-GOGR | 20 (40 μL) | 200 μL |
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| RP35BA-20-GORE | 20 (40 μL) | 200 μL |
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| RP35BA-20-GRGO | 20 (40 μL) | 200 μL |
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| RP35BA-20-GRRE | 20 (40 μL) | 200 μL |
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| RP35BA-20-ORGR | 20 (40 μL) | 200 μL |
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| RP35BA-20-REGO | 20 (40 μL) | 200 μL |
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| RP35BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
Gene Details
Gene Symbol: SEMA4A
Gene Name: Semaphorin 4A
Chromosome: CHR1: 156119734-156147542
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RP35 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SEMA4A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping