RP35 FISH Probe
The RP35 FISH probe is designed to hybridize to the RP35 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SEMA4A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SEMA4A-20-RE | 20 (40 μL) | 200 μL |  |
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| SEMA4A-20-GO | 20 (40 μL) | 200 μL |  |
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| SEMA4A-20-GR | 20 (40 μL) | 200 μL |  |
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| SEMA4A-20-AQ | 20 (40 μL) | 200 μL |  |
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| SEMA4A-20-DIG | 20 (40 μL) | 200 μL |  |
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| SEMA4A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
Gene Details
Gene Symbol: SEMA4A
Gene Name: Semaphorin 4A
Chromosome: CHR1: 156119734-156147542
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RP35 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SEMA4A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping