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ROS1 Break Apart FISH Probe

Empire Genomics’ ROS1 Break Apart FISH Probe is designed to flank the ROS1 gene and is typically used for detecting ROS1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
ROS1BA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
ROS1BA-20-AQOR 20 (40 μL) 200 μL
ROS1BA-20-GOGR 20 (40 μL) 200 μL
ROS1BA-20-GORE 20 (40 μL) 200 μL
ROS1BA-20-GRGO 20 (40 μL) 200 μL
ROS1BA-20-GRRE 20 (40 μL) 200 μL
ROS1BA-20-ORGR 20 (40 μL) 200 μL
ROS1BA-20-REGO 20 (40 μL) 200 μL
ROS1BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: ROS1

Gene Name: ROS Proto-oncogene 1, Receptor Tyrosine Kinase

Chromosome: CHR6: 117609529-117747018

Locus: 6q22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Comprehensive Genomic Profiling of Malignant Effusions in Patients with Metastatic Lung Adenocarcinoma

In this study, the utility of performing targeted next-generation sequencing (NGS) on malignant effusions from patients with metastatic lung adenocarcinoma was investigated. NGS is a high throughput technology, which utilizes a small sample input, but the suitability of NGS analysis for tissue-free cytology samples such as malignant body fluids is not well understood. In order to investigate the adequacy of NGS on liquid biopsies of MLA, targeted NGS was performed using custom target panels consisting of many oncogenes. Additional non-NGS molecular tests were performed on the effusion samples, including fluorescence in situ hybridization (FISH) analysis for the oncogene ROS1, using a break-apart FISH probe manufactured by Empire Genomics.
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Product Details

Product: ROS1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ROS1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping