RGS14 FISH Probe
The RGS14 FISH probe is designed to hybridize to the RGS14 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RGS14-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RGS14-20-RE | 20 (40 μL) | 200 μL |  |
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| RGS14-20-GO | 20 (40 μL) | 200 μL |  |
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| RGS14-20-GR | 20 (40 μL) | 200 μL |  |
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| RGS14-20-AQ | 20 (40 μL) | 200 μL |  |
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| RGS14-20-DIG | 20 (40 μL) | 200 μL |  |
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| RGS14-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RGS14
Gene Name: Regulator Of G Protein Signaling 14
Chromosome: CHR5: 176784843-176799599
Locus: 5q35.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RGS14 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RGS14-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping