RFXANK FISH Probe
The RFXANK FISH probe is designed to hybridize to the RFXANK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RFXANK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RFXANK-20-RE | 20 (40 μL) | 200 μL |  |
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| RFXANK-20-GO | 20 (40 μL) | 200 μL |  |
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| RFXANK-20-GR | 20 (40 μL) | 200 μL |  |
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| RFXANK-20-AQ | 20 (40 μL) | 200 μL |  |
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| RFXANK-20-DIG | 20 (40 μL) | 200 μL |  |
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| RFXANK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: RFXANK
Gene Name: Regulatory Factor X Associated Ankyrin Containing Protein
Chromosome: CHR19: 19303007-19312678
Locus: 19p13.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RFXANK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RFXANK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping