RFX5 FISH Probe
The RFX5 FISH probe is designed to hybridize to the RFX5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RFX5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RFX5-20-RE | 20 (40 μL) | 200 μL |  |
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| RFX5-20-GO | 20 (40 μL) | 200 μL |  |
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| RFX5-20-GR | 20 (40 μL) | 200 μL |  |
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| RFX5-20-AQ | 20 (40 μL) | 200 μL |  |
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| RFX5-20-DIG | 20 (40 μL) | 200 μL |  |
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| RFX5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RFX5
Gene Name: Regulatory Factor X5
Chromosome: CHR1: 151313115-151319769
Locus: 1q21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RFX5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RFX5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping