RET FISH Probe
The RET FISH probe is designed to hybridize to the RET gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RET-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RET-20-RE | 20 (40 μL) | 200 μL |  |
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| RET-20-GO | 20 (40 μL) | 200 μL |  |
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| RET-20-GR | 20 (40 μL) | 200 μL |  |
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| RET-20-AQ | 20 (40 μL) | 200 μL |  |
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| RET-20-DIG | 20 (40 μL) | 200 μL |  |
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| RET-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. [provided by RefSeq, Sep 2017]
Gene Details
Gene Symbol: RET
Gene Name: Ret Proto-oncogene
Chromosome: CHR10: 43572516-43625797
Locus: 10q11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RET FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RET-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping