RBM8A Break Apart FISH Probe
Empire Genomics’ RBM8A Break Apart FISH Probe is designed to flank the RBM8A gene and is typically used for detecting RBM8A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
RBM8ABA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
RBM8ABA-20-AQOR | 20 (40 μL) | 200 μL | ||
RBM8ABA-20-GOGR | 20 (40 μL) | 200 μL | ||
RBM8ABA-20-GORE | 20 (40 μL) | 200 μL | ||
RBM8ABA-20-GRGO | 20 (40 μL) | 200 μL | ||
RBM8ABA-20-GROR | 20 (40 μL) | 200 μL | ||
RBM8ABA-20-GRRE | 20 (40 μL) | 200 μL | ||
RBM8ABA-20-REGO | 20 (40 μL) | 200 μL | ||
RBM8ABA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: RBM8A
Gene Name: RNA Binding Motif Protein 8A
Chromosome: CHR1: 145507556-145513535
Locus: 1q21.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: RBM8A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RBM8A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping