RBL1 FISH Probe
The RBL1 FISH probe is designed to hybridize to the RBL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RBL1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RBL1-20-RE | 20 (40 μL) | 200 μL |  |
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| RBL1-20-GO | 20 (40 μL) | 200 μL |  |
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| RBL1-20-GR | 20 (40 μL) | 200 μL |  |
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| RBL1-20-AQ | 20 (40 μL) | 200 μL |  |
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| RBL1-20-DIG | 20 (40 μL) | 200 μL |  |
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| RBL1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RBL1
Gene Name: RB Transcriptional Corepressor Like 1
Chromosome: CHR20: 35626177-35724410
Locus: 20q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RBL1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RBL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping