RB1 FISH Probe
The RB1 FISH probe is designed to hybridize to the RB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RB1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RB1-20-RE | 20 (40 μL) | 200 μL |  |
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| RB1-20-GO | 20 (40 μL) | 200 μL |  |
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| RB1-20-GR | 20 (40 μL) | 200 μL |  |
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| RB1-20-AQ | 20 (40 μL) | 200 μL |  |
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| RB1-20-DIG | 20 (40 μL) | 200 μL |  |
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| RB1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RB1
Gene Name: RB Transcriptional Corepressor 1
Chromosome: CHR13: 48877882-49056026
Locus: 13q14.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
The Utility of ERBB4 and RB1 Immunohistochemistry in Distinguishing Chromophobe Renal Cell Carcinoma From Renal Oncocytoma
Product Details
Product: RB1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RB1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping