SEARCH OUR PRODUCT CATALOG

RASGRP4 FISH Probe

The RASGRP4 FISH probe is designed to hybridize to the RASGRP4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RASGRP4-20-OR  (Standard Design) 20 (40 μL) 200 μL
RASGRP4-20-RE 20 (40 μL) 200 μL
RASGRP4-20-GO 20 (40 μL) 200 μL
RASGRP4-20-GR 20 (40 μL) 200 μL
RASGRP4-20-AQ 20 (40 μL) 200 μL
RASGRP4-20-DIG 20 (40 μL) 200 μL
RASGRP4-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

Gene Details

Gene Symbol: RASGRP4

Gene Name: RAS Guanyl Releasing Protein 4

Chromosome: CHR19: 38899697-38916945

Locus: 19q13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: RASGRP4 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: RASGRP4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping