RAPGEF5 FISH Probe
The RAPGEF5 FISH probe is designed to hybridize to the RAPGEF5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAPGEF5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RAPGEF5-20-RE | 20 (40 μL) | 200 μL |  |
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| RAPGEF5-20-GO | 20 (40 μL) | 200 μL |  |
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| RAPGEF5-20-GR | 20 (40 μL) | 200 μL |  |
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| RAPGEF5-20-AQ | 20 (40 μL) | 200 μL |  |
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| RAPGEF5-20-DIG | 20 (40 μL) | 200 μL |  |
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| RAPGEF5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
Gene Details
Gene Symbol: RAPGEF5
Gene Name: Rap Guanine Nucleotide Exchange Factor 5
Chromosome: CHR7: 22157907-22396533
Locus: 7p15.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: RAPGEF5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RAPGEF5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping