RANBP2 FISH Probe
The RANBP2 FISH probe is designed to hybridize to the RANBP2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RANBP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| RANBP2-20-RE | 20 (40 μL) | 200 μL |  |
|
| RANBP2-20-GO | 20 (40 μL) | 200 μL |  |
|
| RANBP2-20-GR | 20 (40 μL) | 200 μL |  |
|
| RANBP2-20-AQ | 20 (40 μL) | 200 μL |  |
|
| RANBP2-20-DIG | 20 (40 μL) | 200 μL |  |
|
| RANBP2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RANBP2
Gene Name: RAN Binding Protein 2
Chromosome: CHR2: 109335936-109402267
Locus: 2q13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: RANBP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RANBP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping