RAD50 Break Apart FISH Probe
Empire Genomics’ RAD50 Break Apart FISH Probe is designed to flank the RAD50 gene and is typically used for detecting RAD50 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAD50BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAD50BA-20-AQOR | 20 (40 μL) | 200 μL |
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| RAD50BA-20-GOGR | 20 (40 μL) | 200 μL |
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| RAD50BA-20-GORE | 20 (40 μL) | 200 μL |
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| RAD50BA-20-GRGO | 20 (40 μL) | 200 μL |
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| RAD50BA-20-GROR | 20 (40 μL) | 200 μL |
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| RAD50BA-20-GRRE | 20 (40 μL) | 200 μL |
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| RAD50BA-20-REGO | 20 (40 μL) | 200 μL |
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| RAD50BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
Gene Details
Gene Symbol: RAD50
Gene Name: RAD50 Double Strand Break Repair Protein
Chromosome: CHR5: 131892615-131980313
Locus: 5q31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RAD50 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RAD50-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping