RAD23B FISH Probe
The RAD23B FISH probe is designed to hybridize to the RAD23B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAD23B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RAD23B-20-RE | 20 (40 μL) | 200 μL |  |
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| RAD23B-20-GO | 20 (40 μL) | 200 μL |  |
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| RAD23B-20-GR | 20 (40 μL) | 200 μL |  |
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| RAD23B-20-AQ | 20 (40 μL) | 200 μL |  |
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| RAD23B-20-DIG | 20 (40 μL) | 200 μL |  |
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| RAD23B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: RAD23B
Gene Name: RAD23 Homolog B, Nucleotide Excision Repair Protein
Chromosome: CHR9: 110045543-110094470
Locus: 9q31.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RAD23B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RAD23B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping